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0411U004965,
к.б.н.
18-10-2011
o
Response of carp Cyprinus carpio L. immune system on action of increased concentrations of cadmium and nickel ions.
Drohomyretskaya Yvanna Zynovevna,
popup.head Mazepa Maria Andreevna
popup.opponent Стародуб Микола Федоровия
popup.opponent Діденко Геннадій Васильович
Дисертація присвячена вивченню впливу іонів важких металів на показники неспецифічної резистентності Cyprinus carpio. Проведено комплексний аналіз реакцій клітинних та гуморальних факторів неспецифічної резистентності Cyprinus сarpio за дії підвищених концентрацій кадмію і нікелю та отримано нові дані про загальні закономірності функціонування імунної системи риб у відповідь на дію токсикантів. Встановлено накопичення іонів кадмію і нікелю в органах і тканинах риб за умов експозиції їх у середовищі з підвищеними концентраціями даних металів. Виявлено цитотоксичну дію іонів важких металів на лейкоцити риб, яка проявлялась в пошкодженні цитоплазми і ядер бластних та зрілих форм імунокомпетентних клітин, а також в зменшенні морфометричних показників паличкоядерних і сегментоядерних нейтрофілів, таких як довжина та ширина клітини, площа ядра, клітини та цитоплазми. Виявлено, що іони важких металів призводили до істотних змін популяційного складу лейкоцитів у кровотворних органах (нирці, селезінці) та периферійній крові.
2011-10-18
2020-04-04
Updated: 2025-12-07
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