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0412U002647,
к.мед.н.
29-05-2012
o
Prophylactics of pregnancy, delivery and postpartum period complications in pregnant with diffuse non-toxic goiter.
Bulik Lapisa Michaylivna,
popup.head Davidova Yulia Volodymirivna
popup.head Tsipkun Anatolіy Grigorovich
popup.opponent Камінський Вячеслав Володимирович
popup.opponent Венцківська Ірина Борисівна
Дисертація присвячена одній з актуальних проблем акушерства - зменшенню частоти акушерських та перинатальних ускладнень у вагітних з дифузним нетоксичним зобом (ДНЗ) шляхом розробки комплексу лікувально-профілактичних заходів на підставі оцінки тиреоїдного гомеостазу, функціонального стану фетоплацентарного комплексу, імунного та психоемоційного стану. У вагітних з ДНЗ встановлені істотні порушення цих показників, а саме, порушення фетоплацентарного комплексу, про що свідчило пригнічення його гормональної функції, погіршення матково-плацентарно-плодової гемодинаміки; значне підвищення особистісної та реактивної тривожності; підвищення рівня прозапальних цитокінів та титру антитиреоїдних антитіл до тиреоїдної пероксидази. Відзначений вплив некоригованого гіпомікроелементозу та зниження медіани йодурії на частоту виникнення ускладнень вагітності та погіршення стану плода. Запропонований комплекс лікувально-профілактичних заходів, спрямованих на корекцію виявлених гормональних розладів та покращення психічного стану вагітних, що дозволило зменшити частоту ускладнень у матері і плода.
2012-05-29
2020-04-04
Updated: 2025-12-08
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