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0419U001055,
к.мед.н.
18-12-2018
o
Intensive care of neuro-hemodynamic disorders in cancer patients with superior vena cava syndrome.
Pilipenko Sergiy Oleksandrovich,
popup.head Krutko Evgenii Nikolaevich
popup.opponent Кобеляцький Юрій Юрійович
popup.opponent Хижняк Анатолій Антонович
В дисертації теоретично обґрунтовано та представлено нове вирішення питання діагностики та методу інтенсивної терапії порушень нейро-кардіо-гемодинаміки у онкологічних хворих з синдромом верхньої порожнистої вени, спрямованих на зменшення кількості перед- та післяопераційних ускладнень і зниження летальності при цьому синдромі. На основі вивчення цієї проблеми встановлено, що більш ніж в 90% випадків, що призводять до синдрому верхньої порожнистої вени, виявляються злоякісні пухлини. На частку раку легень припадає 85%. У більшості випадків - це дрібноклітинний або плоскоклітинний рак легень. Летальність при СВПВ досягає 95 %. На підставі вивчення частоти і варіантів видів синдрому верхньої порожнистої вени, встановлено, що при раку легень СВПВ зустрічається у 84% випадків, при лімфопроліферативних пухлинах 13%, при інших видах пухлин у 4% випадків. В передопераційному періоді порушення з боку нейро-кардіо-гемодинаміки визначалися у 93% хворих з СВПВ. Комплексне використання та впровадження запропонованих методів діагностики та інтенсивної терапії у хворих з СВПВ дозволило знизити летальність в 1,4 рази (Р? 0,05); ішемічне ушкодження головного мозку в 1,2 рази (Р? 0,05); зростання стабільності гемодинаміки в 2,7 рази (Р? 0,05).
2018-12-18
2020-04-03
Updated: 2025-12-21
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