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0493U002048,
к.фарм.н.
29-01-1993
o
Попович Валерий Павлович,
popup.head Жогло Ф.А.
popup.opponent Гриценко А.М.
popup.opponent Мусиянович В.М.
Объект исследования: Плоды рябины обычной, липо- та гидрофильный комплексы, полиэкстракт из плодов рябины обычной и лекарственная форма полиэкстракта-капсулы. Цель исследования: Теоретически обосновать и разработать рациональную технологию суммарных лекарственных препаратов из плодов рябины обычной. Методы исследования и аппаратура: Спектрофотометрия, фотоколориметрия, потенциометрия, газовая и колонковая хроматография, эмиссионно-спектральный анализ. Спектрофотометр "СФ-26", фотоколориметр "КФК-2", газовый хроматограф "CHROM-5", анализатор аминокислот "ААА-881", спаренные спектрографы "ИСП-30" и "ДФС-13". Теоретические результаты и новизна: На основании алгоритма получения лекарственных препаратов из плодов рябины обычной разработана комплексная технология их переработки. Практические результаты и новизна: Впервые получен и стандартизирован суммарный лекарственный препарат-полиэкстракт, липо- и гидрофильный комплексы из плодоврябины обычной. Отработана технология экстемпорального изготовления водных вытяжек, масляного экстракта и экстракционной мази из плодов рябины обычной. Предмет и степень внедрения: Разработаны проекты временных фармакопейных статей на полученные лекарственные препараты, методика изготовления и анализа отвара из плодов рябины обычной. Эффективность внедрения: Получено разрешение фармакологического комитета МОЗ Украины на клиническое исследование "Сорбикомплекс 0,25 и О,5 г в капсулах". Сфера (область) использования: Аптеки, контрольно-аналитическкие лаборатории ВО "Фармация", фармацевтические предприятия, ВУЗы и НИИ фармацевтического профиля.
1993-01-29
2020-05-17
Updated: 2025-12-07
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