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0499U003164,
к.мед.н.
16-11-1999
o
Influence of heavy metals compounds (cadmium, lead, thallium and mercury) on system of regulation of bloot aggregate state and tissue fibrinolysis
Podolyan Svitlana Klymivna,
popup.head Мислицький Валентин Францович
popup.opponent Третяк Наталія Миколаївна
popup.opponent Стежка Василь Ананійович
popup.opponent Ельський Віктор Миколайович
Встановлено, що субхронічна інтоксикація хлористими солями Cd, Tl, Pb, Hg викликає у тварин розвиток синдрому дисемінованого внутрішньосудинного зсідання крові (ДВЗ) з первинною активацією тромбоцитарно-судинного гемостазу (ТСГ). Доведено, що препарат ММ-706 (стабільний негалогенізований аналог простацикліну) знижує індекс спонтанної агрегації тромбоцитів (ІСАТ) та зменшує процент адгезивних тромбоцитів (ПАТ) внаслідок дезагрегаційної і мембранопротекторної дії, що дозволяє використовувати цей препарат, як патогенетичний спосіб корекції виявлених змін.
2001-04-03
2021-03-17
Updated: 2025-12-08
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