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0505U000406,
д.мед.н.
29-06-2005
o
Remodeling of the left ventricle and changes of the inheart hemodynamic during the phase of heart failure in patients with ischemic and inflammatory affections of the myocardium.
Chervonopіska Olena Mykhajlivna,
popup.head Kovalenko Volodymyr Mykolajovych
popup.opponent Воронков Леонід Георгійович
popup.opponent Єна Лариса Михайлівна
popup.opponent Фуркало Сергій Миколайович
Дисертацію присвячено актуальній проблемі сучасної кардіології - вдосконаленню ранньої діагностики СН у хворих з ішемічним та запальним ураженнями міокарда на основі використання комплексного ультразвукового трансторакального дослідження серця. Доведено широкі можливості імпульсно-хвильової допплерографії в оцінці ефективності лікувальних втручань у ранні та відділені терміни. На основі цього методу простежено перебіг структурно-функціональної перебудови лівих камер серця у пацієнтів зі стабільними формами ІХС внаслідок реваскуляризації міокарда ЛШ після планового коронарного стентування. Визначено роль феномена мітральної регургітації у розвитку дилатації камери ЛШ при хронічному ішемічному ураженні міокарда. Охарактеризовано діастолічне наповнення ЛШ за типом анормального розслаблення міокарда та рестриктивний тип діастолічного наповнення ЛШ як ехокардіографічні синдроми, що відображають періоди компенсації та/чи декомпенсації ремоделювання при СН. Доведено, що зміни діастолічної функції ЛШ (параметри трансмітрального діастолічного потоку, структурно-функціонального стану ЛП, об'ємні та геометричні показники ЛШ у фазу діастоли) не залежать від впливу етіологічного фактора і відображають загальні закономірності ремоделювання при СН та являються його ранніми діагностичними критеріями.
2005-06-29
2020-04-04
Updated: 2025-12-08
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