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Information × Registration Number 2112U001624, Article popup.category Thesis Title popup.author popup.publication 01-01-2012 popup.source_user Сумський державний університет popup.source http://essuir.sumdu.edu.ua/handle/123456789/34951 popup.publisher Sumy State University Description Hydroxyapatite (Ca10(PO4)6(OH)2, HAp) is materials mainly known for its special ability to contact bone tissue. Nanostructures on implant surfaces, a coating composed of nano-HAp particles on Ti, have aroused increasing research interest in the biomedical field. In this study, we prepared HAp nanocrystal coated Ti surface by plasma surface modification and wet chemical method and then evaluated biological behavior of MC3T3-E1 on the HAp coated on plasma modified Ti surface. Nano-size crystals of sintered HAp were uniformly coated on polyacrylic acid (PAA) deposited Ti surface through the ionic interaction between calcium ions on the HAp nanocrystal and carboxyl groups on the PAA/Ti. In vitro cell tests revealed surface modification of Ti surface with HAp nanocrystal significantly improved the proliferation and growth of the osteoblastic MC3T3-E1 cells and induced them to differentiate at an enhanced level. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/34951 popup.nrat_date 2025-05-12 Close