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Information × Registration Number 2113U001625, Article popup.category Thesis Title popup.author popup.publication 01-01-2013 popup.source_user Сумський державний університет popup.source http://essuir.sumdu.edu.ua/handle/123456789/35430 popup.publisher Sumy State University Description Photoacoustic imaging has been widely studied as a deep biological tissue imaging modality combining optical absorption and ultrasonic detection. It enables multi-scale high resolution imaging of optical absorbing intrinsic molecules as well as exogenous molecules. Gold nanoparticles have the primary advantages of large absorption cross section and bioconjugation capability for the imaging contrast agents. In order to design the photoacoustic imaging agents for enhancing the contrast with high specificity to targeted molecules and / or cell, we measured and analyzed time-of-flight photoacoustic signals of aqueous solutions of various shapes and sizes of gold nanoparticles. The signal intensities were sensitive to the shapes and sizes of the gold nanoparticles. We found a strong photoacoustic signal of the polyhedral gold nanoparticle due to the localized surface plasmon resonance. The experimental results derive the strategy of designing the optimum photoacoustic contrast agents. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/35430 popup.nrat_date 2025-05-12 Close