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Information × Registration Number 2116U004807, Article popup.category Thesis Title popup.author popup.publication 01-01-2016 popup.source_user Сумський державний університет popup.source http://essuir.sumdu.edu.ua/handle/123456789/46494 popup.publisher Springer Description Objective: Pathological mineralization (ectopic calcification) is an often finding in papillary thyroid carcinoma (PTC). The concept of pathological mineralization in papillary thyroid carcinoma included psammoma’s bodies, bone formation, stromal and vascular calcification. Osteopontin (OPN) is a glyco-phosphoprotein that is expressed and secreted by numerous human cancers. Osteopontin is upregulated at sites of pathologic, ectopic calcification—presumably at least in part to inhibit debilitating mineralization in these soft tissues. We investigated the expression of OPN and her correlation with pathological mineralization in PTC. popup.nrat_date 2025-05-12 Close