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Information × Registration Number 2118U003958, Article popup.category Thesis Title popup.author popup.publication 01-01-2018 popup.source_user Сумський державний університет popup.source https://essuir.sumdu.edu.ua/handle/123456789/87383 popup.publisher Sumy State University Description Diabetes mellitus (diabetes mellitus) is a group of metabolic diseases is determined by hyperglycemia, which is the result wrong insulin action, or two factors together. One of the chronic complications of diabetes is diabetic osteopathy, which pronounced from moderate osteoporosis to spontaneous fractures of the tubular bones. Metabolic changes that occurs in diabetes mellitus lead to a violation of the processes of remodeling of bone tissue. In condition shortage of insulin the activity of osteoblasts decreases, and the osteoclast activity, on the contrary, increases due to this bone reabsorption intensifies. With diabetes, the processes of demineralization of bones are clearly expressed. At the diabetes, the processes of demineralization of bones are clearly expressed. Aim: The purpose:to explore the changes in the chemical composition of long tubular bones in aloxans-induced rats in native diabetic ranges. popup.nrat_date 2025-05-12 Close