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Information × Registration Number 2118U003969, Article popup.category Стаття Title popup.author popup.publication 01-01-2018 popup.source_user Сумський державний університет popup.source https://essuir.sumdu.edu.ua/handle/123456789/80871 popup.publisher Hindawi ''Disease Markers'' Description As it is well known, endothelial dysfunction plays an important role in the development of common cardiovascular diseases and their complications. One of the main pathogenetic pathways of endothelial dysfunction development is an increased formation and biological activity of the powerful vasoconstrictor and proinflammatory peptide endothelin (ET-1), which mediates own effects via two pharmacologically distinguishable receptor subtypes, endothelin A (ETA) and endothelin B (ETB) receptors, respectively. popup.nrat_date 2025-05-12 Close