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Information × Registration Number 2123U000832, Article popup.category Стаття Title popup.author Pliuta I. popup.publication 31-01-2023 popup.source_user Національний медичний університет імені О. О. Богомольця popup.source http://ir.librarynmu.com/handle/123456789/5537 popup.publisher Ukrainian Scientific Medical Youth Journal Description The number of patients with non-varicose acute gastrointestinal bleeding who need anticoagulants has increased in the last decade. The choice of method and amount of safe therapy in case of acute gastrointestinal bleeding is complicated. A reasonable optimal balance of therapy between hypo- and hypercoagulant components was determined on the basis of an objective assessment of risk factors for re-bleeding and thromboembolic complications. A council of surgeons, resuscitators and cardiologists decided on the rationality of anticoagulant therapy and its scope. With a low risk of recurrent bleeding and a high risk of thromboembolic complications, hemostatic therapy (tranexamic acid, ethamsylate) was combined with the introduction of low molecular weight heparin (bemiparin) in prophylactic doses. An important parameter for the appointment of conservative therapy were thromboelastography. The data obtained indicate the safety of hemostatic and thromboprophylactic therapy (the level of re-bleeding did not differ from the level of bleeding without the use of low molecular weight heparins, according to the literature). Stroke was observed in only 1 patient. The complexity, multifactorial and diversity of clinical conditions of patients with acute gastrointestinal bleeding indicates the need for further study of the treatment problem. popup.nrat_date 2024-06-02 Close