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Information × Registration Number 2123U009248, Article popup.category Стаття Title popup.author popup.publication 01-01-2023 popup.source_user Сумський державний університет popup.source https://essuir.sumdu.edu.ua/handle/123456789/95266 popup.publisher Izdatel'stvo Elm Description The article analyzes literary sources on the study of the toxic effects of methotrexate in the treatment of various diseases and examines scientific data on methods of preventing their development. According to the literary information, the main toxic effects of methotrexate manifest as damage to the liver, kidneys, bone marrow, lungs, digestive system, and skin. Methotrexate exhibits pronounced embryotoxic and teratogenic effects. Monitoring of blood test parameters and selection of an optimal dose will minimize methotrexate toxic effects and help in achieving success in the treatment. popup.nrat_date 2025-05-12 Close