Search academic texts

Information × Registration Number 2125U003013, Article popup.category Стаття Title Morphometric analysis of the structural changes in the venous bed of the testes in cases of diabetes and portal hypertension (AI translated) popup.author Konovalenko S.Kritsak M.Dzevulska I.Ihnatishchev M.Kaminskyi R.Gargula T.Konovalenko S.Kritsak M.Dzevulska I.Ihnatishchev M.Kaminskyi R.Gargula T. popup.publication 01-01-2025 popup.source_user Національний медичний університет імені О. О. Богомольця popup.source http://ir.librarynmu.com/handle/123456789/16394 popup.publisher Rom J Diabetes Nutr Metab Dis, 32 (2) Description The subject of this study is the venous bed, which has been found to exhibit functional and structural changes in response to increased pressure in the portal system and metabolic disorders in diabetes mellitus in the testes. However, this area has been the subject of insufficient study. The aim of this study was to perform a morphometric analysis of the venous bed of the testes in conditions of portal hypertension and diabetes mellitus. The testes of 46 white male rats were morphologically studied and divided into four groups. The diameter of the postcapillary venules and venules of the left testis increased in portal hypertension by 8.9% (p<0.001) and venules by 10.7% (p<0.01), while in diabetes, the increase was 4.5%. (p<0.001) and 2.3% (p<0.05), and in combined lesions, respectively, increased by 9.8% (p<0.001) and 16.3% (p<0.01 The outer diameter of the venous vessels of the right testis in portal hypertension statistically significantly (p<0.001) increased by 5.2%, in experimental diabetes – by 2.8% (p<0.05), and in combined lesions – by 6.8% (p<0.001). Conversely, the internal diameter of the venous vessels of the right testis exhibited a marked increase of 8.1% (p<0.001) in the setting of portal hypertension, 4.4% (p<0.01) in diabetes, and a substantial 10.6% (p<0.001) in the presence of a combination of diseases. The height of venous vessel endothelial cells, the diameter of their nuclei, and the nuclear-cytoplasmic index of the right testis exhibited minor alterations in the modeled pathologies, thereby indicating the stability of structural cellular homeostasis. Diabetes mellitus has been observed to induce a pronounced structural alteration of the venous vascular bed of the testes, particularly when combined with portal hypertension. popup.nrat_date 2025-11-05 Close