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Information × Registration Number 0212U006175, 0111U004828 , R & D reports Title Antitumor efficiencyand mechanisms of photodynamic and radiation therapy mediated by nanocomposites of colloidal gold with cytotoxic lectin and porphyrins popup.stage_title Head Usatenko Alexander Vasilуevich, Registration Date 27-02-2012 Organization Institute of economy and to the management, Open International university of human development "Ukraine" popup.description2 The project objective is to elucidate the mechanisms of destruction of tumor tissue under the influence of the original version of photodynamic therapy (FDTP), biotherapy (BT) and radiotherapy of tumors (PT) with the use of new porphyrin nanobiocomposites colloidal gold with a cytotoxic lectin.One of the ways to enhance the sensitivity of tumor tissue to the light emission due to the increased accumulation of photosensitizers in it, may be the use of nanotechnology approaches, in particular aggregation photosensitizing drugs with gold nanoparticles.An important aspect of nanocomposite materials is dependent on the number of their properties located on the cluster surface atoms, which essentially reflected in the biological activity of drugs made from nanoparticles.During the second phase of performance carried out spectroscopic studies of singlet oxygen (1O2) under photoirradiation of the ternary complex of colloidal gold porphyrins (hematoporphyrin, chlorin E6) and the cytotoxic lectin. Product Description popup.authors Бебешко Володимир Григорович Гамалія Микола Федорович Потебня Григорій Платонович Щербаков Олександр Борисович popup.nrat_date 2020-04-02 Close