Registration Number
0120U104294,
(
0220U104249
0221U105883
0221U106629
)
R & D request
Title
The influence of antiviral and thrombolytic drugs on the model membranes of viral particles and eukaryotic cells.
Head
Dovbeshko Galyna I., д.ф.-м.н.
Registration Date
17-10-2020
Organization
Institute of Physics of National Academy of Sciences of Ukraine
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In this interdisciplinary project we will study molecular mechanisms of action of amphiphilic drugs, which are used in the COVID-19 therapy, on the lipid membranes of viral particles and cells infected by viruses. The relevance of the project is based on the fact that lipid membranes of membrane-containing viruses, including SARS-CoV-2, are still studied insufficiently. In particular, it is not known if lipid components of viral particles could be targeted by the drugs and whether it is possible to achieve selectivity of such targeting by utilizing different physical properties of viral and cell membranes. This work will be the first where these questions are addressed.
popup.nrat_date
2024-12-10
