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Information × Registration Number 0120U104883, ( 0221U101020  0222U001056  0224U000419  ) R & D request Title Enzymes of post-translational modifications of microtubule proteins as targets for inhibition of the excitability of primary nociceptive neurons Head Karpov Pavlo A., Доктор біологічних наук Registration Date 13-11-2020 Organization Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine popup.description1 The main goal of the project is to determine the role of enzymes involved in posttranslational modifications (PTM) of microtubule elements, in the modulation of ion channels of excitable cells of the Peripheral Nervous System (PNS) and the search for pharmacological means of influencing these molecular targets. The ability to regulate the activity of enzymes such as HDAC6, aTAT1, TTLL1 or ELP3 complex, can be used for innovative correction of disorders that occur in chronic pain conditions of various etiology. popup.nrat_date 2024-12-10 Close