Registration Number
0121U111087,
( 0221U105129 0222U005036
) R & D request
Title
Investigation of the effect of cellular factors in a population of tumor stem cells in culture tumor mikrospheroid
Head
Sydorenko Mykhailo V.,
Registration Date
20-05-2021
Organization
State Institution Department of Biotechnical Problems of Diagnostics of the Institute of Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine
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To determine the morphological, proliferative and molecular features of subpopulations of multicellular tumor spheroid cells; biochemical mechanisms of influence of substances of cellular origin and anticancer drugs on subpopulations of cells of multicellular tumor spheroid; to investigate the presence and percentage of tumor stem cells in a multicellular spheroid under different conditions of the microenvironment; to analyze the molecular genetic characteristics of cell subpopulations of the tumor spheroid under the influence of factors secreted by stromal cells.
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2024-12-09
