1 documents found
Registration Number

0123U101110, ( 0224U032361  0225U003486  ) R & D request

Title

The role of the thiol-disulfide system in the implementation of neurodestruction/neuroprotection mechanisms and the development of pharmacological modulation pathways after prenatal hypoxia

Head

Belenichev Ihor Fedorovych, Доктор біологічних наук

Registration Date

15-02-2023

Organization

Zaporizhzhya State Medical University

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Еxperimentally substantiate the use of modulators of thiol-disulfide system (glutathione, glutaredoxine, and derivatives of selenium, tiazotate, and cysteine), as well as heat shock factor 1 (HSF-1) in the management of consequences of prenatal CNS hypoxia on the basis of experimental data revealing the role of the thiol-disulfide system in the interruption of NO-; IL-1b; ROS-dependent mechanisms of neurodestruction and excitotoxicity and SH/HSP70 – mediated regulation mechanisms of endogenous neuroprotection.

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2024-12-09

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The role of the thiol-disulfide system in the implementation of neurodestruction/neuroprotection mechanisms and the development of pharmacological modulation pathways after prenatal hypoxia
Head: Belenichev Ihor Fedorovych. The role of the thiol-disulfide system in the implementation of neurodestruction/neuroprotection mechanisms and the development of pharmacological modulation pathways after prenatal hypoxia. Zaporizhzhya State Medical University. № 0123U101110
1 documents found

Updated: 2025-07-06


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