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Information × Registration Number 0123U104256, ( 0224U031448  0224U032711  ) R & D request Title Development of semi-industrial protocols for the synthesis of functionalized carboranes – a promising platform for biomedical applications Head Rassukana Yuliia V., Доктор хімічних наук Registration Date 18-10-2023 Organization Institute of Organic Chemistry NAS of Ukraine popup.description1 1. To elaborate convenient cost-efficient protocols for semi-industrial scale synthesis of ortho- meta- and para-disubstituted carboranes. 2. To design a chemical toolbox for the synthesis of functionalized carboranes for needs of medicinal chemistry and material science. 3. To conduct ADME/PK profiling of the carborane-based analogues of the compounds with well-studied biological activity. 4. To prove the concept of the bioisosteric relationships between carborane and benzene cores. popup.nrat_date 2024-12-09 Close