Registration Number
0202U006726,
0100U000015
, R & D reports
Title
Influence of eucosanoids content change into blood on healing of experimental myocardial infarction.
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Head
Semenova T.V.,
Registration Date
11-12-2002
Organization
State Medical University named after M. Gorky
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In research shown, that application blokator of synthesis leukotrienes (Korvitin - soluble Quercetin) or synthetic analogues prostaglandins (PG - PG Е2 (Prostenon) and F2аlphа (Enzaprost)) changes a stress-reaction, modulates flow of restoration processes and myocardial infarction (MI) cicatrization result. Introduction quercetin brings to limitation stress-reactions over, application PG Е2 is attended with lowering of reactivity, and application PG F2аlphа by its rise. Influence eucosanoids on restoration processes attached to by MI to a great extent depends on primary organism reactivity. Application of Quercetin and PG Е2 brings to optimization healing of MI on background of raised reactivity and makes heavier of MI attached to initial normo- and organism hyperactivity, which finds oneself by development postinfarction aneurysm. Application PG F2аlphа leads to optimization of MI healing on background of lowered reactivity and makes heavier of MI attached to initial normo- and organism hyperactivity.Influence eucosanoids on organism reactivity and healing of MI necessary to take into account attached to arrangement elaboration of its cure.
Product Description
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2020-04-03
