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Information × Registration Number 0203U000357, 0199U003956 , R & D reports Title Enzymes and metabolites of polyunsaturated fatty acids cascades of plants, animals and man. (mechanisms of action,regulation of activity,models of enzyme activity. Synthesis and investigation of the new lipoxygenase effectors. Enzyme synthesis and direction modification of fatty acids) popup.stage_title Head Butovich I.A., Registration Date 31-01-2003 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The aerobic oxidation of linoleyl alcohol (LAL) by lipoxygenase (LOX) in the presence of phosphatidic acid, SDS and 4-hydroxy-TEMPO was studied. The very ability of LOX to oxidize uncharged substrates like polyunsaturated fatty alcohols in the presence of activators is of fundamental interest. Newly discovered details of the oxidation of LAL by LOX show that the enzyme is capable of a direct and relatively specific oxidation of unusual and virtually insoluble substrates, that opens new horizons in discovering new lipoxygenase products in plants and animals and in studying new potential biological regulators of lipid nature biosynthesized by lipoxygenase.5635 Product Description popup.authors popup.nrat_date 2020-04-02 Close