Registration Number
0203U000423,
0100U000300
, R & D reports
Title
Synthesis analysis of antimicrobal, antiviral and fungistasis properties of the new derivatives of geterocyclic compounds, brimstone containing alkelic and aromatic derivatives, phosphorus and dephosphorus acids.
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Head
Shumejko V.M.,
Registration Date
05-02-2003
Organization
Institute of Pharmacology and Toxicology Academy of Medical sciences of Ykraine
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Is synthesized 82 BAS - derivative azotkeeping of heterocycles (pirole, pyridine, pyrimidine,quinazoline); brimstonekeeping, (sultones, and sulphonates); phosphorus keeping (Natrii phosphases, phosphanes both ethersand hydrazines of phosphoric acid) and aromatic derivative galer of an acid). The design was carried out on a principle of design of clones of fissible frames. In a structure of a new means Vosurel have come dymethylureophenes an acid, 2,4-dyamino-5-(31,41,51,-trimethoxibenzil)pirimidin. And water soluble metal- silicate mix Vodozol (TS-У46.15.055-94). At fulfilment of researches for a GOST 12.1.007-76,it has properties 3 classes of danger and shows antiinflammatory activity. The analysis of the antimicrobal activityVosurel has shown the the means was fissible in relation to all of tests -microorganisms. In delution 1:6 it oppressed increase E.coli, P.aeruginosa, E.faecalis and in delution 1:10 - S.aureus, C.albicans, C.utilis.The minimum inhibiting concentration is on equal 0.01 LD50.The gear of specific operating Vosurel conditioned by destruction of membranes of bacterias, inhibition of functions of a breeding of the genetical vehicle of a pathogenic microflora and stimulation of not specific protection.
Product Description
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2020-04-03
