Registration Number
0204U000358,
0100U006336
, R & D reports
Title
Physical mechanisms of the interactions of new synthesized biologically active compounds with hydrated DNA
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Head
Maleev Vladimir Yakovlevich,
Registration Date
02-02-2004
Organization
Institute of Radiophisics and Electronics NASU
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The aim of the investigation is the study of molecular mechanisms of interactions of new biologically active compounds (actinocin derivatives) with hydrated DNA in dependence on AT/GC compositon, water content in system DNA - biologycally active compound and of the degree of irradiation damage of macromolecular structure. Biophysical task is the investigation of structure and energetic parameters of DNA-biologically active compound-water complexes by the methods of experimental physics and computer simulations.
Product Description
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2020-04-03
