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Information × Registration Number 0204U005158, 0102U003999 , R & D reports Title New ensemblrs of hydrogenated azoloazines popup.stage_title Head Orlov V., Registration Date 26-03-2004 Organization Kharkov National University named after V.N.Karazin popup.description2 Object of investigation - dihydro- and tetrahydro derivatives of 1,2,3- and 1,2,4-triazolo-, tetrazolo[1,5-a]pyrimidines; imidazo[1,5-b]piridazines; 1-phenyl-3-pirazolylpropiophenons; 7-methyl-5pirazolyl-5H-tetrahydrotiazolo[3,2-a]pirimidin-3-on-6-carboxylic acids. The main aim of this project - to increase the synthetic accessibility of dihydro- and tetrahydro- derivatives of 1,2,3- and 1,2,4-triazolo-, tetrazolo[1,5-a]pyrimidines via the regioselective heterocyclization reactions of a-amino and 1,2-diamonoazoles with a,b-unsaturated carbonyl compounds, their synthetic precursors and equivalents; investigation of chemical structure and Methods of investigation: organic synthesis, physico-chemical analysis, including IR and NMR spectroscopy, X-ray structural analysis, elemental analysis. The main conclusion: The peculiarities of the reactions of a-aminoazoles with a,b- unsaturated carbonyl compounds, their analogs and synthetic precursors were studied. The comparative analysis of several physico-chemical factors onto the imino-enamine tautomeric equilibrium of dihydroazolopyrimidines was made. The new pathways of the interactions of the aromatic unsaturated ketones and their synthetic equivalents with substituted aminoazoles were elucidated. The applications field of science- organic chemistry. Product Description popup.authors popup.nrat_date 2020-04-02 Close