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Information × Registration Number 0205U000739, 0102U000393 , R & D reports Title Expression of matrix metalloproteinases and hypoxia-inducibleble factor in malignant gastric and pancreatic tumors: impact on metastasis and disease outcome popup.stage_title Head Osinsky S.P., Registration Date 09-02-2005 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 It was observed that increase of hypoxia level in tumor is accompanied by enhancement of gelatinase A and B activity. It was shown that hypoxia level, expression of HIF-1alpha and microvessel density in primary tumor may be proposed as independent prognostic factors of disease outcome. High level of tumor hypoxia is a marker for an unfavorable prognosis in patients with No. Detection of tumor cells in bone marrow and peripheral blood of oncogical patients with Mo might be useful for predicting the early metastasis. Product Description popup.authors popup.nrat_date 2020-04-02 Close