Registration Number
0205U000739,
0102U000393
, R & D reports
Title
Expression of matrix metalloproteinases and hypoxia-inducibleble factor in malignant gastric and pancreatic tumors: impact on metastasis and disease outcome
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Head
Osinsky S.P.,
Registration Date
09-02-2005
Organization
R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
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It was observed that increase of hypoxia level in tumor is accompanied by enhancement of gelatinase A and B activity. It was shown that hypoxia level, expression of HIF-1alpha and microvessel density in primary tumor may be proposed as independent prognostic factors of disease outcome. High level of tumor hypoxia is a marker for an unfavorable prognosis in patients with No. Detection of tumor cells in bone marrow and peripheral blood of oncogical patients with Mo might be useful for predicting the early metastasis.
Product Description
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2020-04-03
