Registration Number
0206U000960,
0102U003053
, R & D reports
Title
Experimental and clinical rationale for the new method of treatment of female hyperandrogenic infertility in order of its implementation into the clinical practice
popup.stage_title
Head
Reznikov Olexandr Grygorovуch,
Registration Date
09-02-2006
Organization
V.P.Komisarenko Institute of Endoсrinology and Metabolism
popup.description2
Object: morphofunctional state of female and male physiological systems in rats. Aim of the work: further elaboration and experimental and clinical background for the new method of treatment of hyperandrogenic infertility in females, and study of mechanism of antiandrogen flutamide action concerning the restoration of fertility in experimental animals. Methods and apparatus: physiological, morphological, raddioimmunological; -spectrometers, microscope, low temperature refrigerator, computer. Results and their novelty: on the model of anovulation caused by androgen excess in female rats the restoration of sexual cyclicity, morphofunctional state of reproductive system and fertility after flutafarm tablets application in a dose of 10 mg/kg was found. The safety of Flutafarm under single and multiple use has been proved. Degree of introduction: publications, reports. Field of application: endocrinology, gynecology.
Product Description
popup.authors
popup.nrat_date
2020-04-02