Registration Number
0209U008752,
0107U001190
, R & D reports
Title
To investigate the functional alterations of the neuro-muscle apparatus in progressive muscle dystrophy and to study the possibility its correction by allogenic fetal tissues
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Head
Tsymbaluk Vitaliy Ivanovich,
Registration Date
15-12-2009
Organization
SI "Institute of neurosurgery named after acad. A.P. Romodanov of Academy of Medical Sciences of Ukraine"
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The object of study - patients with progressive muscular dystrophy, which were treated with allogenic fetal myoblasts. The purpose of study - improve the results of treatment of motive disorders in patients with progressive muscular dystrophy with allogenic fetal myoblasts. Methods of study - clinical neurological, immunological, biochemical and statistical methods. The diagnostic complex was designed to evaluate the efficacy of treatment of patients with PMD under intramuscular injections of allogenic fetal myoblasts. We proved, that intramuscular injections of allogenic fetal myoblasts improve physical development in children, decrease signs of muscular degeneration and do not evoke signs of cellular aggression from immune system. Positive changes of rates at electrode-needle ENMG and muscles function are observed during 6-12 months after the treatment initiated. The efficacy of treatment is confirmed with biochemical data (changes of rate of enzyme CFK) and with improvement of muscles function in children, mostly in an age group up to 7 years, in case that allogenic fetal myoblasts were injected at least 4-5 times. The application of allogenic fetal myoblasts allowed us to improve the results of treatment of patients with PMD. The branch of use is neurosurgery.
Product Description
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Василовська Світлана Володимирівна
Вербовська Світлана Анатоліївна
Вотякова Ірина Андріївна
Гужовська Наталія Вадимівна
Давидова Тетяна Іванівна
Лісяний Микола Іванович
Маркова Ольга Володимирівна
Пічкур Леонід Дмитрович
Пічкур Наталія Олександрівна
Руденко Валентина Андріївна
Синявська Людмила Федорівна
Цимбалюк Віталій Іванович
Чайка Ольга Іванівна
Чеботарьова Лідія Львовна
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2020-04-02
