Registration Number
0210U001046,
0105U001580
, R & D reports
Title
Development of original syntheses of functional derivatives of azaheterocycles - potential bioregulatores
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Head
Brovarets V.,
Registration Date
19-01-2010
Organization
Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine
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Approaches to synthesis of new derivatives of azoles, azines and their condensed systems using enamides, enamidonitriles, unsaturated azlactones, sulphonylsubstituted enimidoylchlorides and enheterocumulenes were found. New areas of application of amidophenacylating reagents were discovered, for obtaining derivatives of mononuclear azaheterocycles and their condensed analogues. New approaches to synthesis of condensed pyrimidines were found on the basis of phosphonium ylides and salts. Testing a number of the synthesized compounds on immunomodulating, antiblastic and bactericidal properties and also in-the-field testing the "Methiur" preparate on antidepressant activity were carried out.
Product Description
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Баля А.Г.
Василенко О.М.
Виджак Р.М.
Виноградова Т.К.
Головченко О.В.
Демидчук Б.А.
Зябрєв В.С.
Ключко С.В.
Мітюхін О.П.
Неделькіна Н.Н.
Пільо С.Г.
Панчишин С.Я.
Попільниченко С.В.
Попович Т.П.
Прокопенко В.М.
Сливчук С.Р.
Туров К.В.
Хутова Б.М.
Шабликін О.В.
Юдіна Т.М.
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2020-04-02
