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Information × Registration Number 0210U003032, 0107U000921 , R & D reports Title Study of the peculiarities heart arrhythmia formation, its clinical manifestations, myocardium structure and functions state in clean-up workers after Chernobyl accident and elaboration of the managements for treatment efficacy increasing popup.stage_title Head Khomazjuk Inna, Registration Date 14-01-2010 Organization State Institution "Research Center for Radiation Medicine of Academy of Medical Sciences of Ukraine" popup.description2 Subject of inquiry: 651 clean-up workers after Chernobyl disaster (CWCD): 289 patients with extrasystolia, 42 - recurrent atrial fibrillation (AF), 80 - permanent atrial fibrillation are main group, 240 - without heart arrhythmias (HA) (compared group), 133 non-irradiation patients with HA (control group). 6286 case histories of clean-up workers after Chernobyl disaster (СWCD), which were hospitalized to cardiology department in 1986-2007. Primary and current control during hospital treatment is conducted for 287 patients, protracted supporting therapy at 154 from them. Goal: Identify features of the formation of arrhythmia, its clinical manifestations, changes of structural and functional state of the myocardium, physical working capacity in clean-up workers after Chernobyl disaster and to develop activities aimed at improving the effectiveness of treatment. Methods: clinical, analysis of irradiation influence as well as others risk factors, Holter electrocardiography and heart rate variability monitoring, dopplerechocardiography, bicycle ergometry, statistical technology. Results: Detected a gradual increase in the frequency of HA for the past 2 times, it was associated with increasing age, the frequency of cardiovascular diseases. Priority in the etiological structure had ischemic heart disease, hypertension, and their combination. Found that the participants in the CWCD since May 1986, who worked in the watch mode, the frequency of HA was more than 2 times greater than that of participants in 1987. In persons exposed in the dose range of 25-50 sZv frequency of HA was higher by 5,1%. Were identified clinical manifestations, electrocardiographic features, change the structures and functions of the heart, exercise tolerance, which were typical for CWCD with HA. There have been unsubstantiated concept of treatment and measures aimed at improving the treatment of HA and associated changes. Been studied the effects of short-and long-term complex treatment of CWCD with HA and the development of measures aimed at improving the effectiveness of treatment. Been developed guidelines, innovations, diagnostic extrasystolic arrhythmia, a model of treatment of paroxysmal atrial fibrillation. Efficacy. It was proved that the application of established activities provided antiarrhythmic effect, prevention / regression of structural changes, improve heart function, increase exercise tolerance, prevention of cardio-vascular complications, in terms of adherence to treatment. By results the 25 articles, 12 doсlads, new method (patent № 40038, 25.03.09), methodical guidelines are prepared. Product Description popup.authors Златогорська Ж.М. Курсіна Н.В. Настіна О.М. Сидоренко Г.В. Хомазюк І.М. popup.nrat_date 2020-04-02 Close