Registration Number
0210U003247,
0107U001107
, R & D reports
Title
Synthesis of monomers and initiators - saccharide derivatives for obtaining biocompatitible and biodegradable polymers
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Head
Voronov Stanislav, Доктор хімічних наук
Registration Date
27-01-2010
Organization
Lviv Polytechnic National University
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Suggested methodology and elaborated methods for synthesis of new classes saccharides containing monomers, peroxides and surface active compounds with predicted properties. Their heat resistance, polymerization ability and surface activity were investigated. New types of water soluble carbochain surface-active saccharides-containing oligomers, as well as stable biotolerant colloid systems from nanoparticles with engrafted to the surface saccharides fragments were obtained on the basis of synthesized compounds. Utilization of obtained surface-active saccharides-containing oligoperoxides as templates and modificators permits on the basis of magelithe with biocompatible shell to obtain simultaneously golden and super magnetic nanoparticles. On the basis of obtained surface modificated nanoparticles together with Institute for Cell Biology of NASU were created materials able to recognize and separate cells pathology. Branched saccharides chain functional oligomers obtained by graft-copolymerization of saccharides-containing monomers are able to immobilize water insoluble microbe substances with their physiological activity preservation. This permits to create new water-soluble nontoxic nanodimensional systems for goal drug delivery.
Product Description
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Іжик О.М.
Борзенков М.М.
Вострес В.Б.
Вуйцик Л.Б.
Гаргай Х.І.
Гевусь О.І.
Долинська Л.В.
Дончак В.А.
Заіченко О.С.
Кінаш Н.І.
Кочубей В.В.
Мітіна Н.Є.
Надашкевич З.Я.
Ріпак Л.М.
Скачко С.В.
Флейчук Р.І.
Хабурський Я.
Харламова М.Б.
Холод М. О.
Штомпель В.І.
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2020-04-02
