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Information × Registration Number 0210U004266, 0109U006432 , R & D reports Title System of the control cytotoxic and mutagen properties of immunobiological preparations popup.stage_title Head Ushkalov V. A., Registration Date 06-05-2010 Organization The State Science-control institute of Biotechnology and microorganism's strains popup.description2 Literary search is lead and world analogues of standards and systems of studying of toxic and mutagen action immunobiological preparations are analysed. Search of optimum tests - systems іn vіtro and іn vіvo for research cytotoxic and mutagen displays immunobiological preparations has shown the most informative cultures of cells of an animal origin and Drosophіla melanogaster Mg. For research cytotoxic and mutagen immunobiological preparations in sector of maintenance of cultures of cells SSCIBSM the following methods have been developed and entered: I Definition cytotoxic actions of a preparation on cells of an animal origin; II Definition of toxic action of a preparation on a reproduction of cells of an animal origin; III Definition sharp mutagen actions of a preparation on modelling animals; IV Definition chronic mutagen actions of a preparation on models іn vіvo during several generations. It is lead researches cytotoxic and mutagen action of five inactivated bacterial vaccinal preparations. Product Description popup.authors Бабкін М.В. Лаврик О.А. Тімченко Д.С. Ушкалов В.О. popup.nrat_date 2020-04-02 Close