Registration Number
0210U007251,
0104U010501
, R & D reports
Title
Immune-genetic, epidemiologic, pharmacogenetic and clinical microbiology aspects of interactions between host and pathogen system in the course of tuberculosis infection in rising tuberculosis incidence rates
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Head
Bazhora Yuri, Доктор медичних наук
Registration Date
23-11-2010
Organization
Odessa state medical university
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The techniques of simple molecular genetic methods to determine resistance to isoniazid (katG gene) and rifampicine (rpoB) in the patient's sputum is proposed. The technique of determination of epidemiologically dangerous Beijing family of M. tuberculosis is offered, it is shown that infecting by this strand is the factor of unfavorable course of the disease. Acquired immunodeficiency state in pregnant women with tuberculosis is proved to be formed as a result of cellular component of immune response. It is shown that the study of biological fluids of patients with tuberculosis by laser correlation spectroscopy allows to differentiate the pathological process from the norm and to estimate the integral indicators of homeostasis, which is important to predict the character of the disease course.
Product Description
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Антоненко Катерина Олексіївна
Антоненко Петро Борисович
Асмолов Олександр Костянтинович
Бажора Юрій Іванович
Годован Владлена Володимирівна
Зубаренко Олександр Всеволодович
Комлевий Олександр Миколайович
Кресюн Валентин Йосипович
Левицька Нелля Анатоліївна
Лобанов Олексанр Кирилович
Пашолок Сергій Петрович
Польова Светлана Петрівна
Тимчішин Олег Львович
Филюк Віталій Васильович
Чеснокова Марина Михайлівна
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2020-04-02