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Registration Number

0211U009781, 0111U004837 , R & D reports

Title

Palladium phosphonates in new technologies for the diagnosis and treatment of a number of cancer diseases.

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Head

Pekhnyo Vasyl Ivanovych,

Registration Date

23-12-2011

Organization

National Academy of Scienіses of Ukraine, Council of Productive Forces Studies of Ukraine

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Novel complex compounds of palladium with diphosphonic (HEDP, MDP) and aminodiphosphonic (AEDP) acids have been synthesized. The composition, structure, stability and pH ranges of complex formation have been determined. It has been proved that HEDP and MDP form with Pd complexes of equimolar composition, in which the ligands are coordinated to Pd by two oxygen atoms of phosphonic groups. Pd forms with AEDP complexes of equimolar composition and bisligand complexes, in which one or two AEDP molecules are coordinated to Pd by a nitrogen atom and an oxygen atom of phosphonic group. It has been shown that the complexes studied show anticancer activity.

Product Description

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Дудко Анатолій Вікторович
Козачкова Олександра Миколаївна
Царик Наталія Віталіївна