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Information × Registration Number 0212U000615, 0108U010141 , R & D reports Title Genetic aspects of malignant tumors in children and young people in Western Ukraine popup.stage_title Head Hnateyko Oleh, Registration Date 01-03-2012 Organization Scientific-research institute of Hereditary pathology popup.description2 In the group of 26 women with abnormalities of reproductive function (eclampsia, preeclampsia) found 2 (7.7%) families burdened oncopathology cases (lung cancer, lymphogranulomatosis) and determined the frequency of gene variants polimornyh folatnoho exchange. In couples with spontaneous abortions and missed pregnancies and first trimester of history found an increased frequency of allele a high gene expression of IL-10 (G-allele) compared with the frequency of allele low expression (A-allele) - 61.8% and 38.2 %, respectively. Only one seven "I (11%) through the woman was burdened onkopatolohiyeyu. In 30 families residing in the town of Amber, malignant tumors were found in 20 (66.7%) families. In 30 families residing in the village. Stetseva,-in 14 (46.7%) families. Malignant tumors of various etiologies met in these families from 1 to 4 cases. A bank of DNA samples from 16 individuals with suspected syndrome Nijmegen and 5 samples - by Louis-Bar syndrome. The results of family analysis showed that among the six studied families with family diffuse polyposis of the colon, which numbered 98 people, symptoms were found in 19 (19.4). Congenital malformations, along with gastro-intestinal manifestation of the disease was found in 9 (47.3%) - congenital hypertrophy of retinal pigment epithelium, abnormalities of teeth (olihodontiya), high arched palate and kidney - structures (cysts), the number of (additional amount) and defects cups (congenital hydronephrosis). Product Description popup.authors Єфіменко Олена Костянтинівна Акопян Гаяне Рубенівна Віштак Наталія Валентинівна Гельнер Надія Володимирівна Гнатейко Олег Зіновійович Кіцера Наталія Іванівна Кеч Наталія Романівна Лозинська Марія Ростиславівнв Маркевич Наталія Володимирівна Терпиляк Ореста Ігорівна Тиркус Марта Ярославівна Третяк Богдан Іринейович Чорна Лілія Богданівна popup.nrat_date 2020-04-02 Close