Registration Number
0212U005283,
0110U006169
, R & D reports
Title
The effect of cultured autologous cells on restoration of tendon structure under experimental tendopathy.
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Head
Gryschenko Valentyn I.,
Registration Date
22-05-2012
Organization
Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine
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The research object is cultures of multipotent mesenchymal stromal cells (MSCs) of rats bone marrow, tendons. The research aim is to establish the possibility of using autological multipotent mesenchymal stromal cells bone marrow (MSCs) for treatment of experimental tendinopathy. The research methods are cultural one, light microscopy, histological and biochemical analysis, surgical methods with laboratory animals. The results of the research work - the possibility of autological MSCs for the treatment of degenerative tendon injury was explored. Histological studies have shown that MSCs have a positive effect on the recovery of damaged tendons, which was manifested by normalization of the structural and functional organization of the Achilles tendon. The biochemical analysis of blood serum of rats with degenerative tendon injury demonstrated the positive dynamics of inflammatory process flow of animals after therapy with autological MSCs. The application area is biology and medicine.
Product Description
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Волкова Наталія Олександрівна
Гончарук Олена Іванівна
Гордієнко Наталія Миколаївна
Грищенко Валентин Іванович
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2020-04-02
