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Information × Registration Number 0213U000215, 0111U002130 , R & D reports Title Stadying fibrogenesis predictors and their role in chronic hepatitis progressing in children popup.stage_title Head Berezenko V.S., Registration Date 25-01-2013 Organization State organization "Institute of pediatrics, obstetrics and gynecology NAMS of Ukraine" popup.description2 On the basis of these studies found that 43 % of children with chronic hepatitis C (HGC) and 10 % of chronic hepatitis B (HGB) had elevated levels of serum ferritin, iron overload occurred only in children with chronic hepatitis C (12 %). 75 % of children with HGB postponed iron in macrophages and hepatocytes, which correlated with the severity of fibrosis in the liver tissue and in the activity of hepatitis. Diagnosed in 30 % of patients with CHB iron deposition mainly in macrophages had no connection with the severity of fibrosis. Manifestations oxsidative stress had 60% of patients with chronic viral hepatitis. The degree of degradation of proteins was highest in patients with HGC with an active inflammatory process in the liver and disease duration more than 5 years. As a marker of advanced liver fibrosis proposed rate reserve-adaptive capabilities of the organism. Product Description popup.authors Диба М.Б. Задорожна Т.Д. Мостовенко Р.В. Тищенко В.К. Філатова О.Б. popup.nrat_date 2020-04-02 Close