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Information × Registration Number 0213U001066, 0111U000754 , R & D reports Title The creation of recommendations to the genetical testing of the predisposition to cancer of mamma and medical-genetical counceling of women, exposed to ionizing radiation due to Chernobyl accident. popup.stage_title Head Klymenko Sergiy, Доктор медичних наук Registration Date 11-01-2013 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Оbjectives - algorithms for genetic testing mutations in the genes BRCA1 and BRCA2 risk carrying for women participating in the liquidation of Chernobyl catastrophe consequence. Purpose - to conduct the analysis of sensitivity and specificity of calculating risk carrying of mutations in the genes BRCA1 and BRCA2 methods for women participating in the liquidation of Chernobyl catastrophe consequence. Methods - medical-genetical consultation,molecular genetical investigations, psychological testing, mathematic statistics. The comparative analysis of BRCA1 and BRCA2 carrying prediction algorithms ((Penn II, Myriad and IBIS) was conducted, using parameters of sensitivity and specificity. Algorithm Myriad has been recognized as more efficient and easier to use in parameters of sensitivity and specificity. Product Description popup.authors Бичкова Г.М. Рибченко Л.А. Скибан Г.В. Тимшина А.М. Ярошенко Н.Є. popup.nrat_date 2020-04-02 Close