Registration Number
0213U001069,
0112U002407
, R & D reports
Title
Radiomodifying study properties of N-stearoylethanolamine in experiments on rats
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Head
Derevyanko Ludmyla Petrivna; Tal'ko Viktoriya Vasylivna,
Registration Date
11-01-2013
Organization
State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine "
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Object: prooxidant and antioxidant systems, functional status gonadal axis of adult female rats (60). Objective: To verify the changes pro-, antioxidant systems and the functional state of gonadal axis in female rats exposed to different conditions of N-stearoylethanolamine. Methods: biochemical, enzymeimmunoassay, statistics. It was found that when rats were irradiated at the dose of 2.0 Gy, and both schemes of N-stearoylethanolamine at the dose of 50 mg / kg (before and after the exposure) in blood plasma significantly reduced the concentration of TBA-active products, the 11-ACS, increased activity of catalase, glutathioneperoxidase, concentrations of progesterone, estradiol, compared with irradiated animals. These changes indicate that, in the conditions of application of preparation exhibits radiomodifying (radioprotective) effect.
Product Description
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Атаманюк Н.П.
Булавицька В.М.
Дерев'янко Л.П.
Родіонова Н.К.
Талько В.В.
Фролова Н.О.
Шелковський М.В.
Яніна А.М.
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2020-04-02
