Registration Number
0213U006731,
0113U005063
, R & D reports
Title
The development of new antiepileptic compounds to inhibit hippocampal seizures
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Head
Isaeva Olena Valentynivna,
Registration Date
25-12-2013
Organization
Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine
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As a result of stage № 1 of research work "Investigation of temporal lobe epilepsy models and recording of control data for further screening (SET-1) compounds" were conducted studies of temporal lobe epilepsy models. Such models of epileptiform activity as low-magnesium model, gabazine model of seizures and 4-aminopyridine model were tested during investigation. It was determined the character and manifestation of seizures for each model, the ability to stop emerging phenomena using different screening agents and the basic mechanisms involved in the induction and maintenance of this type of activity.
Product Description
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Ісаєв Дмитро Сергійович
Венгренюк Артем Васильович
Максимюк Олександр Петрович
Романов Артур Костянтинович
Савотченко Аліна Володимирівна
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2020-04-02
