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Registration Number

0213U008045, 0108U011005 , R & D reports

Title

Differential lipidcorrective treatment in the patients with ischemical heart disease.

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Head

Zolotariova Natalia Artemovna,

Registration Date

03-12-2013

Organization

Odesa National Medical University

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The study involved 455 patients with stable angina, and arterial hypertension. Atorvastatin reduced total cholesterol, ?-lipoprotein, low density lipoprotein (LDL) levels, reduced endothelial dysfunction, but did not affect triglyceride (TG) and high density lipoproteins (HDL). Adding fenofibrate corrected all lipid parameters except HDL, but had a negative effect on lipid peroxidation and increased the frequency of side effects. Consumption of "Berezovska" mineral water eliminated treatment-induced side effects. The use of statins with omega-3 PUFA reduced the level of total cholesterol, LDL, ULDL and TG levels. Metabolic cytoprotector mexicor enhanced the effect of statin therapy and lead to normalization of TG. Adding magnetic therapy also contributed to HDL level elevation. Discovered dynamics of protein and non-protein SH-, S-S groups and the SH/SS coefficient in patients with different forms of ACS was specific enough for being used as additional diagnostic criteria

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Волковинська Тетяна Василівна
Золотарьова Ксенія Олегівна
Золотарьова Наталія Артемівна
Ковалевська Людмила Андріївна
Костюшова Наталія Володимировна
Медянка Юрій Степанович
Пахомова Олена Олегівна
Писковацький Павло Михайлович
Романченко Максим Ігорович
Соломко Олена Володимирівна
Юрлов Владислав Михайлович