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Information × Registration Number 0213U008254, 0111U007442 , R & D reports Title Risk factors, pathogenesis, particulary of treatment, prognosis and prevention of cardiorenal syndrome in patients with ischemic heart disease popup.stage_title Head Kuryata Olexandr, Доктор медичних наук Registration Date 02-01-2014 Organization Dniepropetrovsk State Medical Academy popup.description2 Objective: to determine the status of the coronary circulation and kidney function in patients with coronary artery disease , especially progression of CHF with preserved systolic function based on the study of cardiac hemodynamics , endothelial function , renal function , to develop ways to improve the effectiveness of treatment and measures to improve the safety of interventional studies. Object of study: 432 patients , including 376 patients with chronic ischemic heart disease between the ages of 40 to 75 years (mean age - 57,7 ± 0,50 years) who underwent coronarography from 2006 to 2011 and 56 patients with CHF I-III functional class (according to the classification of the New York Heart Association (NYHA)) with preserved LV systolic function in age from 45 to 69 years (mean age - 74,80 ± 2,66 years) due to coronary artery disease. Methods: physical, instrumental, biochemical, immuno. Based on a comprehensive clinical, laboratory and instrumental studies revealed the mechanism of influence of low and isoosmolar contrast agents for vascular endothelium, microalbuminuria and ?- 2 -microglobulin . Revealed that renal barer CHF patients with preserved systolic function parameter exceeds conventional albumin and molecular weight corresponds to the range of 120-140 kDa. Practical recommendations for individual choice of optimal pharmacotherapy options based on the determination of the clinical status of the patient with coronary artery disease and heart failure based on renal function. Results of research put into practice and therapeutic cardiology department of Dnepropetrovsk, Zaporozhye, Krivoy Rog, Poltava. Branch of service - and therapeutic cardiology departments of hospitals, gerontological preventive health care. Keywords : coronary heart disease , chronic heart failure , renal function , coronary endothelium, treatment, prevention. Product Description popup.authors Бардаченко Наталя Ігорівна Гейченко Валентина Петрівна Караванська Ілона Лоранівна Карапетян Карп Гургенович Курята Олександр Вікторович Кушнір Юлія Сергіївна Мірошниченко Ганна Сергіївна Митрохіна Ольга Сергіївна Філіппова Олександра Юріївна Фролова Євгенія Олександрівна popup.nrat_date 2020-04-02 Close