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Information × Registration Number 0213U008309, 0111U010128 , R & D reports Title To study the mechanisms of pathological changes of the circulatory system and their impact on physical activity in patients with bronchial asthma popup.stage_title Head Feshchenko Yuriy Ivanovich, Registration Date 15-01-2014 Organization SO "National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine" popup.description2 Object: 75 patients with bronchial asthma. Aim : improving quality of life in patients with asthma by examining violations of the functional state of the cardiorespiratory system in a graduated exercise and develop ways of preventing their progression . Methods: clinical, functional , and statistical . Was found that in patients with bronchial asthma has worsened biophysical parameters of deformability and osmotic resistance of red blood cells, namely on the red cell membrane, a decrease in the relative charge ( RH ) and an increase in the relative potential gradient ( RPG ) . At mild asthma all of these changes are seen only during exacerbation of the disease, normalize in remission. At moderate BA is a steady rise and fall of RH and RPG with the formation of pathological morfoform and microcytosis , regardless of the phase of the disease. Also found that in patients with bronchial asthma with a slight persistent course, is not variations in the performance of cardio - vascular system at maximum effort , maximum level of performance of the load was reduced by 10.5 % during exacerbation and 2.5 % - in remission. 100% of patients with moderate asthma exacerbation there is a decrease of metabolic cost of work performed ( MET) to an average of (4,8 ± 1,6) kcal / kg and the level of work done to an average of (68,6 ± 4 7 )%, (0,6 ± 0,2) W / kg (92,3 ± 6,8) Wat. In the remission of the disease are reduced : The metabolic cost of work (MET ) to (4,7 ± 1,3) kcal / kg, exercise capacity (W) to (78,6 ± 4,3)% and (1,2 ± 0.1 ) W / kg. Sphere of application - рulmonology Product Description popup.authors Адамчук Олександр Ігорович Бегоулєва Жанна Борисівна Бриньова Тетяна Іванівна Канарський Олександр Анатолійович Крилач Олена Ігорівна Курик Леся Михайлівна Меренкова Евгенія Олександрівна Пархоменко Наталія Володимирівна Примушко Наталія Андріівна РолікЛюдмила Володимирівна Сінгаєвський Мирослав Богданович Турчина Інна Петрівна Фещенко Юрій Іванович popup.nrat_date 2020-04-02 Close