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Information × Registration Number 0214U006215, 0113U002981 , R & D reports Title Molecular design, synthesis, biological testing and study of mechanism of action of функціоналізованих of клатрохелатів iron(II) as inhibitors of some therapeutically important enzymes popup.stage_title Head Dubey Igor, Доктор хімічних наук Registration Date 19-02-2014 Organization Institute of Molecular Biology and Genetics popup.description2 The effect of a series of iron(II) clathrochelates on the activity of T7 RNA-polymerase in the in vitro transcription assay. High inhibiting effect of some complexes at nanomolar concentrations was found. Among the tested compounds, five active inhibitors of transcription were found with IC50 in the range 500-960 nM and especially efficient complex with ІС50 = 150 nM. Product Description popup.authors Ільченко М.М. Дубей Л.В. Костіна В.Г. Кузів Я.Б. Негруцька В.В. popup.nrat_date 2020-04-02 Close
R & D report
Molecular design, synthesis, biological testing and study of mechanism of action of функціоналізованих of клатрохелатів iron(II) as inhibitors of some therapeutically important enzymes
Head: Dubey Igor. Molecular design, synthesis, biological testing and study of mechanism of action of функціоналізованих of клатрохелатів iron(II) as inhibitors of some therapeutically important enzymes. (popup.stage: ). Institute of Molecular Biology and Genetics. № 0214U006215
1 documents found

Updated: 2026-03-27


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