Registration Number
0214U008763,
0113U007578
, R & D reports
Title
Creation of mew anaestetic drugs, based on pharmacologic agents, which blocked proton-senced channels
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Head
Boyko Oleksandr Mikolajovich,
Registration Date
02-10-2014
Organization
Taras Shevchenko Kiev university
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Using a comprehensive simulation regulators considering potential target structures and tasks on the synthesis of the compounds simulated revealed a series of new spoluk- inhibitor-sensitive proton channels ASICs, proposed a series of chemical nohvyh skefoldiv - receptor agonists tsilovoho. Established Library inhibitor (12 000 compounds) from which part - involved with the existing base compounds synthesized by addition of rantsshe realized Methodics of about 300 compounds were synthesized for the first time.
Product Description
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Бориско Петро Олександрович
Зозуля Сергій Олексійович
Платонов Максим Олегович
Толмачов АКндрій Олексійович
Юрченко Володимир Володимирович
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2020-04-02
