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Information × Registration Number 0215U000515, 0113U000132 , R & D reports Title Association between MGP and VDR gene polymorphism with the development of ischemic stroke popup.stage_title Head Ataman Alexandr Vasilievich, Registration Date 27-02-2015 Organization Sumy State University popup.description2 Association of polymorphic variants of genes MGP and VDR with atherothrombotic ischemic stroke (AIS) in Ukrainian population was first investigated. Found that the risk of AIS homozygotes for the minor allele of the A/A (G-7A polymorphism MGP) is 2.6 times higher than that of the primary carriers of allele - G/G and G/A. Found an association between AIS and polymorphic variants G-7A MGP gene in females. In women gomomozigot on minor allele A/A, the risk of stroke 6.6 times higher than that of the primary carriers of allele (G/A + G/G). The influence of single nucleotide polymorphisms of vitamin D receptor gene on the clinical characteristics of atherothrombotic ischemic stroke was studied. It was determined that in patients who have F/F, b/b, a/a, a/A, and T/T genotypes, statistically significant association between hypertension and IS development exists. Product Description popup.authors Атаман Олександр Васильович Бороденко Анастасія Олександрівна Гарбузова Вікторія Юріївна Дубовик Євген Іванович Прасол Дарія Олександрівна Шимко Карина Ашотівна popup.nrat_date 2020-04-02 Close