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Registration Number

0215U003241, 0112U000024 , R & D reports

Title

Study of the development of onco-epidemiological process in population of Ukraine after the Chernobyl accident

Head

Shchepotin Igor Borisovych,

Registration Date

22-01-2015

Organization

Ukrainian Research Institute of Oncology and Radiology

Description

Object of study - registered in the database of National Cancer Registry incident cases and deaths from malignant neoplasms in population of Ukraine and oblasts affected by the consequences of Chernobyl accident. Objective - to study the dynamics of onco-epidemiological process in whole Ukraine and selected administrative areas, to assess the potential impact gained by the consequences of the Chernobyl accident after 25 years. Method of investigation - medical informatics, descriptive epidemiology, mathematical statistics, mathematical modeling. The increase of incidence of almost all cancers with 1.5 excess of rate of growth of incidence rates on the contaminated territories was found. The largest growth rate of cancer incidence of patients of both sexes recorded in the urinary organs, for men - in prostate cancer, for women - in uterine body, breast and thyroid cancer, that caused exceeding medium Ukrainian incidence rates 1.5-3 times. It was found that during the first decade after the accident, the mortality rates in the contaminated areas increased for up to 25.2% against 10.6% in whole Ukraine, and then decreased. Exceeding of medium Ukrainian mortality rates in the contaminated areas was observed for urinary cancers (2-3 times) and for hemoblastoses (1.2 times). Increase of cancer incidence in Ukraine by 0.8% in men and 6.3% in women until 2020 is projected; in the contaminated areas the increment could be 1.5-4 times higher. Age structure of the incidence reallocated towards younger age groups in cancer of cervix, prostate and thyroid glands, lymphatic and hematopoietic tissue. Level of survival rates of patients with cancer of digestive organs, urinary organs, malignant lymphoma, breast and uterine body (n women), prostate (in men) in the contaminated areas was lower than in Ukraine, that allows to assume radiation impact on the course of malignant process. In the contaminated areas level of provided oncological beds was 1.4-2.6 times lower than the normative, coverage by mammography and cytological screening was 1.5-3 times lower than the average in Ukraine that caused high percent of advanced stages in breast cancer and cervical cancer incidence and determines the priorities in anti-cancer activity. CANCER, INCIDENCE RATES, MORTALITY RATES, SURVIVAL RATES, ONCOLOGICAL CARE, CANCER REGISTRY

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Горох Є.Л.
Гулак Л.О.
Куценко Л.Б.
Рижов А.Ю.
Сумкіна О.В.
Федоренко З.П.