Registration Number
0215U004348,
0109U008220
, R & D reports
Title
Stable carbenes and their metal complexes in heterocyclic synthesis and catalysis of organic reactions
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Head
Korotkikh Nikolai Ivanovich, Доктор хімічних наук
Registration Date
05-03-2015
Organization
The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry
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Object of the study is the synthesis of sterically shielded aryl substituted of imidazol-2-ylidenes and 1,2,4-riazol-5-ylidenes and their palladium complexes, synthesis of derivatives on the basis of stable carbenes, catalytic efficiency in the reaction of haloarene hydrodehalogenation. The purpose of the work is synthesis of sterically shielded aryl derivatives of imidazol-2-ylidenes and 1,2,4-triazol-5-ylidenes and their palladium complexes study of the structure and catalytic efficiency of complexes in the reaction of haloarene hydrodehalogenation, transformations of 1,2,4-triazol-5-ylidenes with electrophiles. Methods of the research are synthetic , kinetic , spectral (NMR spectroscopy ) analytical, chromatoghrafical, elemental analysis), quantum chemical, X-ray diffraction study. Basic results. Sterically shielded aryl substituted imidazol-2-ylidenes and 1,2,4-triazol-5-ylidenes and salt palladium complexes on their basis have been synthesized. A monomeric character of palladium complexes of imidazol-2-ylidenes with branched aryl substituents and a dimeric (binuclear) character of complexes with 2,6-diisopropylphenyl (dipp) substituents have been established. The high catalytic effect of sterically shielded complexes with branched aryl substituents relative to dipp-substituted and sterically open. A stable spirocyclic compound a derivative of 1,2,4-triazolo-spiro-pyrrolinthione was synthesized by the reaction of 1,2,4-triazol-5-ylidene with phenylisothiocyanate and dimethyl acethylene dicaroxylate. A new transformation of 4-bromoaniline was found under the alkylation by benzhydrole in the acidic medium that as a result of substitution of bromine to benzhydryl gives 2,4,6-trisbenzhydrylaniline. The data obtained have significance for the preparative synthesis of stable carbenes, transition metal carbene complexes as catalysts of organic reactions and for the heterocyclic synthesis. Scope of application - catalysis of organic reactions, synthesis of carbenes and transition metal carbene complexes, heterocyclic synthesis on the basis of carbenes.
Product Description
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Єня Василь Іванович
Глиняна Наталія Валеріївна
Дорошенко Тетяна Федорівна
Кисельов Артем Вікторович
Кнішевицький Артур Володимирович
Ковач Микола Анатолійович
Короткіх Микола Іванович
Лящук Сергій Миколайович
Орлов Максим Артурович
Раєнко Генадій Федорович
Сабєров Вагіз Шамільйович
Швайка Олесь Павлович
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2020-04-02
