Registration Number
0215U004793,
0114U007011
, R & D reports
Title
Elaboration and implementation of differentiated approaches for the treatment of pelvic organs malignant tumours
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Head
Dubinina Vladlena,
Registration Date
01-12-2015
Organization
Odesa National Medical University
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In the first clinical study analyzed the clinical data of examination and treatment of 55 patients with locally advanced cervical cancer treated with combined radiation therapy on existing clinical guidelines. All patients underwent cervical biopsy before treatment and during radiotherapy until reaching a total focal dose of external beam radiotherapy to the whole pelvis 20 Gy, which contributed to a decrease in proliferation index to 47,3 ± 4,2%. to 22,6 + 4,9% (p <0,05). In the second clinical study was a comparative analysis of 110 clinical cases of ovarian cancer stage IIIA-IIIC,. The criterion for separating patients into groups was selected ovarian sensitivity to platinum drugs. First group consisted of 73 patients with ovarian cancer progression. The second group consisted of 37 patients with lack of disease progression in the treatment within six months of observation.. A significant positive correlation between the presence of cytogenetic abnormalities in patients with ovarian cancer, and malignant ovarian tumors sensitive to chemotherapy drugs platinum..
Product Description
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Дубініна Владлена Геннадіївна
Кузнєцова Ольга Володимирівна
Лисенко Вікторія Володимирівна
Лук'янчук Олег Валерійович
Рибін Андрій Ігорович
Тюєва Ніна Вікторівна
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2020-04-02
